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Preventing Spontaneous Preterm Birth

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Collage of Liz, Phil, Oscar and Felix

Oscar & Felix's story

This year marks what would have been Oscar and Felix’s 10th birthday. In honour of their boys, Liz and her husband Phil, completed 10 fundraising challenges to help raise money for Action and the importance of research into premature birth. 

 We feel their loss every day, but knowing charities like Action are dedicated to funding research to help stop premature birth, so that fewer families face the losses we have, gives us purpose

Liz. (Oscar & Felix's mum)
Professor Rachel Tribe in a hospital hallway smiling

Preventing preterm birth

Professor Tribe and her team at King's College London are developing a new treatment that can help prevent spontaneous preterm birth by modifying the mother’s immune and inflammatory responses during pregnancy. 

In an earlier study, they found that delivering human decidual stromal cells – found in the lining of the womb – during pregnancy can prolong pregnancy in a laboratory model of preterm birth.  

Now the team is testing whether this cell treatment can also delay delivery to help save lives, while also studying the cells’ effects on inflammation and finding the best dosage and timing to maximise its success. If successful, this innovative treatment could ultimately lead to better outcomes for many babies and their families.

Pregnancy-focused research like this is rarely prioritised by government funders in the UK. That’s why supporters like you, who make Action’s work possible, mean so much to researchers like me. 

Professor Rachel Tribe, Action Funded Researcher