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Tourette syndrome: why are some children more prone to tics?

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Around one in every hundred children develops Tourette syndrome.1,2 They have tics, which means that they move, say something or make a sound in a sudden and involuntary way that seems to be totally without purpose. Professor Georgina Jackson, of the University of Nottingham, is studying whether children with Tourette syndrome get tics partly because they’re particularly good at learning habits. Her work could lead to better ways to assess each child’s suitability for behavioural therapies and the development of new treatments that stop children from getting severe tics that continue into adulthood. This could improve children’s lives considerably.

Action Medical Research and Great Ormond Street Hospital Children's Charity are jointly funding this research.

How are children’s lives affected now?

“At first, children with Tourette syndrome, which affects the brain and nervous system, have quite simple tics – for example, they might blink or sniff repeatedly,” says Professor Jackson. “As time goes by, children’s tics tend to become more complex. They might, for example, throw things in class or shout the same word over and over again. Complex tics can be particularly distressing as they can be painful and draw unwelcome attention to the child. To other people, it can seem as if the child is behaving in a bizarre way, or acting inappropriately, on purpose, even though they’re not.”

“Sadly, Tourette syndrome is linked to social isolation, rejection and bullying, and it can be a barrier to learning,” adds Professor Jackson. “Children can also worry about their future – around one third of children find their symptoms carry on throughout their life, but it’s not possible to predict who will be affected in this way.”

How could this research help?

The team aims to improve understanding of how children’s tics develop, and why they often get worse in the first eight years after onset.

The researchers are investigating the theory that children with Tourette syndrome are unusually good – perhaps too good – at learning habits. They’re also exploring whether it’s harder for children with Tourette syndrome to break a habit once it’s been formed. The team is assessing children’s abilities using a specially created computer game.

“Our new computer game could be useful when assessing whether behavioural therapy is suitable for a child,” says Professor Jackson. “Current treatments don’t work for everyone, and medication can have unpleasant side effects, so our findings could also help with our longer term goal of developing new treatments that stop children from getting the more elaborate tics that can continue into adulthood. Tics like this can be particularly detrimental to children’s quality of life. Treatments that stop them could be hugely beneficial.”


1. NHS Choices. Tourette’s syndrome. Website accessed 5 September 2015.



Project LeaderProfessor Georgina M Jackson BA BEd PhD
Project TeamDr Maddie J Groom BSc PhDProfessor Stephen R. Jackson BA PhD
Project LocationDivision of Psychiatry and Applied Psychology, Institute of Mental Health, University of Nottingham
Project duration2 years
Date awarded20 July 2015
Project start date2 November 2015
Project end date10 August 2018
Grant amount£97,651
Grant codeGN2398

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